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Why is the flavour thus dangerous? E-cigarette water contains a large number of different chemical substances, and these vary widely from item to item, said lead author Flori Sassano. She actually is a study task supervisor using the School of NEW YORK College of Medication. Several chemical substances are toxic to human being cells in the lab, however the most toxic seem to be those linked to the flavourings within e-liquids, Sassano said. These chemical substances include vanillin and cinnamaldehyde, which produce the flavours of vanilla and cinnamon respectively. The flavourings have already been approved by the united states Food and Medication Administration for consumption, but it doesn’t mean they may be safe to inhale as vapour from an e-cigarette, Sassano explained.